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Medical Office Building Investing: The Recession-Proof Commercial Real Estate Play

October 26, 2025
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Medical office buildings (MOBs) offer stable cash flow with long-term leases and reliable tenants backed by healthcare demand that’s immune to economic cycles.

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Why Medical Office Buildings Outperform

According to the National Association of Real Estate Investment Trusts (Nareit), medical office buildings have:

  • Average cap rates: 6-8%
  • Occupancy rates: 92%+ (highest of all commercial)
  • Lease terms: 7-10 years (vs. 3-5 for traditional office)
  • Tenant credit quality: Excellent (medical practices rarely fail)

Demographic tailwind: According to the U.S. Census Bureau, 10,000 Americans turn 65 daily, driving healthcare demand through 2030.

Types of Medical Office Properties

Type 1: On-Campus MOB

Location: Adjacent to hospital campus Tenants: Hospital-affiliated physicians, outpatient services Lease structure: Often hospital master lease (strongest credit)

Advantages:

  • Highest quality tenants
  • Lowest vacancy (hospital sends referrals)
  • Premium rents (15-25% above off-campus)
  • Easier financing

Disadvantages:

  • Higher purchase price ($250-350 per sq ft)
  • Hospital may have right of first refusal
  • Competition limited (controlled by hospital)

Disadvantages:

  • Higher purchase price ($250-350 per sq ft)
  • Hospital may have right of first refusal
  • Competition limited (controlled by hospital)

Typical deal:

  • 30,000 sq ft building
  • Purchase: $8.5M ($283/sq ft)
  • Cap rate: 6.5%
  • Lease: 10-year hospital master lease
  • Rent: $28/sq ft triple net

Type 2: Off-Campus Multi-Tenant MOB

Location: Near residential areas, high visibility Tenants: Mix of specialists (ortho, cardio, dermatology, dental) Lease structure: Individual practice leases

Advantages:

  • Lower acquisition cost ($150-220 per sq ft)
  • Rent growth potential (staggered lease expirations)
  • More available properties

Disadvantages:

  • More management intensive
  • Higher tenant turnover risk
  • Tenant improvement costs

Typical deal:

  • 25,000 sq ft building
  • Purchase: $4.5M ($180/sq ft)
  • Cap rate: 7.5%
  • 8 tenants (average 3,000 sq ft each)
  • Average lease: 7 years
  • Rent: $24/sq ft NNN (net, net, net)

Type 3: Single-Tenant MOB

Location: Varies Tenant: Single large practice (20+ providers) Lease structure: Long-term absolute net lease

Advantages:

  • Simplest management (one tenant)
  • Strong credit (established practices)
  • Low cap rates (5.5-7%)

Disadvantages:

  • Single tenant risk (if they leave, 100% vacant)
  • Less rent growth (long-term fixed lease)
  • Lower returns

Market Selection Criteria

Best markets for medical office (per CBRE Healthcare):

Growth markets:

  1. Phoenix, AZ – Retiree migration
  2. Dallas-Fort Worth, TX – Population growth
  3. Tampa-St. Petersburg, FL – Aging population
  4. Nashville, TN – Healthcare hub
  5. Raleigh-Durham, NC – Research triangle healthcare

Key metrics to evaluate:

  • Population 65+: Growing faster than 2%/year
  • Household income: $75k+ median
  • Hospital proximity: Within 3 miles of major hospital
  • Competitors: Under 20,000 medical office sq ft per 1,000 residents

Understanding Medical Office Leases

Lease structures:

1. Gross Lease:

  • Tenant pays flat rent
  • Landlord pays all operating expenses
  • Less common in medical office

2. Modified Gross:

  • Base year established
  • Tenant pays increases above base year
  • Common in multi-tenant buildings

3. Triple Net (NNN):

  • Tenant pays rent + all expenses (taxes, insurance, CAM)
  • Most common in single-tenant MOBs
  • Landlord has minimal expense risk

Typical lease terms:

  • Term: 7-10 years
  • Rent increases: 2-3% annually
  • Renewal options: 2-3 five-year options
  • Tenant improvements: $30-60 per sq ft (landlord paid)
  • Free rent: 3-6 months for buildout

Example lease economics:

  • 5,000 sq ft cardiology practice
  • Base rent: $25/sq ft NNN = $125,000/year
  • 3% annual increases
  • 10-year term with two 5-year options
  • Tenant improvement allowance: $200,000 ($40/sq ft)

Tenant Improvement Considerations

Medical tenants require specialized buildouts:

Common requirements:

  • Plumbing for exam rooms ($10-20k per room)
  • HVAC upgrades (medical-grade filtration)
  • Medical gas systems (oxygen, vacuum)
  • Lead-lined walls (for X-ray rooms)
  • Specialized electrical (imaging equipment)
  • ADA compliance (wider doors, accessible restrooms)

Costs:

  • Standard medical office: $50-80 per sq ft
  • Surgical/imaging suites: $100-150 per sq ft
  • Dental offices: $80-120 per sq ft

Amortization: Built into rent over lease term (landlord recovers cost)

Due Diligence for Medical Office

Essential investigations:

□ Zoning verification: Confirm medical use allowed □ Environmental Phase I: Required by all lenders □ ADA compliance audit: $2,000-5,000, identifies violations □ Rent roll verification: Contact tenants directly □ Insurance requirements: Medical malpractice exposure □ Parking analysis: Medical office needs 4-5 spaces per 1,000 sq ft □ Certificate of Occupancy: Verify square footage □ Review all leases: Personal guarantees? Assignment rights?

Financing Medical Office Buildings

Loan options:

  • CMBS loan: 25-30% down, 7-8%, for $2M+
  • Bank portfolio loan: 30% down, 7.5-8.5%, relationship-based
  • SBA 504: 10% down, for owner-occupied medical practice

Lender underwriting focus:

  • Rent roll stability (prefer leases with 3+ years remaining)
  • Tenant diversity (no single tenant over 30% of income)
  • Location (prefer on-campus or near major hospital)
  • Property condition (deferred maintenance = higher rate)

According to Commercial Mortgage Alert, medical office has lowest default rate of commercial real estate at 0.8%.

Tax Benefits of Medical Office

Depreciation:

  • Building: 39 years
  • Land improvements: 15 years
  • Tenant improvements: Over lease term or 15 years

Bonus depreciation: Cost segregation typically identifies 20-25% of building for accelerated depreciation

1031 Exchange: Medical office to medical office is common strategy for upgrading portfolio

Exit Strategies

Typical hold period: 7-10 years

Exit options:

1. Sale to REIT: Medical REITs actively acquire (Healthpeak Properties, Physicians Realty Trust) Target: Stabilized assets with strong credit tenants

2. Sale to private investor: Strong buyer pool (individual investors, family offices) Medical office seen as “bond alternative”

3. 1031 into larger property: Use equity to upgrade to better location or larger building

Historical appreciation: 3-4% annually (per Green Street Advisors)

The Bottom Line

Medical office best for:

  • Conservative investors seeking stability
  • Those with $1M+ to invest
  • Long-term hold strategy (7-10 years)
  • Desire for passive income

Returns to expect:

  • Cash-on-cash: 8-10%
  • Total return (with appreciation): 10-13%
  • Cap rates: 6-8%
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